Menu
 

Search abstracts


Pharmacokinetics and pharmacodynamics of new purine-2,6-dione–based pde4/7 inhibitors in rats

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: WYSKA, Elzbieta (Jagiellonian University Medical College, Department of Pharmacokinetics and Physical Pharmacy)
  • Co-author(s): Elżbieta Wyska
    Artur Świerczek: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Krzysztof Pociecha: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Marietta Ślusarczyk: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Agnieszka Jankowska: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Grażyna Chłoń-Rzepa: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Maciej Pawłowski: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
  • Abstract:

    Background

    Rheumatoid arthritis (RA) is a debilitating autoimmune disorder for which no fully effective treatment exists. The encouraging results of preclinical studies on selective phosphodiesterase (PDE) 4 inhibitors using animal models of this disease has prompted us to search for new antirheumatic compounds acting as dual PDE inhibitors that

    ..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 13 May 2019

FIP Congresses