Menu
  • Join
  • Login
  • Contact
 

Search abstracts


Pharmacokinetics and pharmacodynamics of new purine-2,6-dione–based pde4/7 inhibitors in rats

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: WYSKA, Elzbieta (Jagiellonian University Medical College, Department of Pharmacokinetics and Physical Pharmacy)
  • Co-author(s): Elżbieta Wyska
    Artur Świerczek: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Krzysztof Pociecha: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Marietta Ślusarczyk: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Agnieszka Jankowska: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Grażyna Chłoń-Rzepa: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Maciej Pawłowski: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
  • Abstract:

    Background

    Rheumatoid arthritis (RA) is a debilitating autoimmune disorder for which no fully effective treatment exists. The encouraging results of preclinical studies on selective phosphodiesterase (PDE) 4 inhibitors using animal models of this disease has prompted us to search for new antirheumatic compounds acting as dual PDE inhibitors that

    ..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses