Pharmacokinetic-pharmacodynamic analyses of glimepiride using rats, and simulations of the effect

• At: Glasgow (Scotland) (2018)
• Type: Poster
• Poster code: POS-PAA-006
• By: KIRIYAMA, Akiko (Doshisha Women’s College of Liberal Arts, Faculty of Pharmaceutical Sciences)
• Co-author(s): Akiko Kiriyama: Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyotanabe, Japan
  Shunsuke Kimura: Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyotanabe, Japan
  Akiko Tanaka: Faculty of Pharmaceutical Sciences, Kobe Pharmaceutical University, Kobe, Japan
  Toshiyasu Sakane: Faculty of Pharmaceutical Sciences, Kobe Pharmaceutical University, Kobe, Japan
  Katsumi Iga: Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts, Kyotanabe, Japan
  
• Abstract:

  Background

  "EN-US">Efficacy/safety of a drug and its plasma concentration are closely correlated. Therefore, it is important to understand the relationship between the drug’s plasma concentration and its effects.

  Methods

  Glimepiride (0.2, 0.5 and 1.0 mg/kg) was intravenously infused for 30 min and blood samples were collected until 300 min for PK and
  ..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login