Pristimerin regulates lipid biogenesis and mtor pathway by activating ampk in colon cancer cells
- At: 2018 FIP Congress in Glasgow (Scotland)
- Type: Poster
- By: YOUSEF, Bashir (Faculty of Pharmacy, University of Khartoum, Department of Pharmacology)
- Co-author(s): Bashir Alsiddig Yousef
Reprogramming of metabolic pathways and enhancements of lipid biogenesis are important features of colorectal cancer cells (CRC). AMP protein kinase (AMPK) is a metabolic sensor that modulates lipid biosynthetic enzymes and mTOR signaling pathway. Pristimerin, a naturally occurring triterpenoid was previously reported by us to exhibit.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.