Enantioselective penetration enhancing effect of carvone on in vitro transdermal permeation of nicorandil

• At: 2008 FIP Congress in Basel (Switzerland)
• Type: Poster
• By: Y.S.R., Krishnaiah (Faculty of Pharmacy, Kuwait University, Kuwait, Kuwait)
• Co-author(s): S.M., Al-Saidan (Faculty of Pharmacy, Kuwait University, KUWAIT, Kuwait)
  A.H., Nada (Faculty of Pharmacy, Kuwait University, KUWAIT, Kuwait)
  
• Abstract:

  Introduction: The objective of the investigation was to study the possible enantioselective penetration enhancing effect of carvone (a chiral terpene) on transdermal drug permeation using nicorandil as a model drug.
  
  Methods: The in vitro permeation study was carried out across excised rat skin using an automated flow-through diffusion apparatus...

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