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Biodegradable hydrogels of recombinant thrombomodulin promotes chronic wound healing

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: TSAI, Jui-Chen (NCKU Research and Development Foundation, Institute of Clinical Pharmacy and Pharmaceutical Sciences)
  • Co-author(s): Yun-Yan Hsu: Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan, Province of China;Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
    Kuan-Lin Liu: Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
    Hsun-Hua Yeh: Institute of Clinical Pharmacy and Pharmaceutical Sciences, National Cheng Kung University, Tainan, Taiwan, Province of China
    Hong-Ru Lin: Department of Chemical and Materials Engineering, Southern Taiwan University of Science and Technology, Tainan, Taiwan, Province of China
    Hua-Lin Wu: Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan, Province of China
    Jui-Chen Tsai
  • Abstract:

    Background

    Thrombomodulin (TM) is a type-I transmembrane glycoprotein expressed on the surfaces of endothelial cells and epidermal keratinocytes. It is known to regulate blood coagulation, inflammation, and cell-cell adhesion.  A recombinant TM, which contains an epidermal growth factor - like domain and serine/threonine-riches domain, has been..

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Last update 13 May 2019

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