Nanoemulsion impregnated films for the transdermal delivery of cyclobenzaprine

• At: Glasgow (Scotland) (2018)
• Type: Poster
• Poster code: POS-FDP-011
• By: LEWIS, Shaila (Manipal College of Pharmaceutical Sciences, Pharmaceutics)
• Co-author(s): Shaila Angela Lewis
  Soniya Kumbham: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  M Vivek Ghate: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  P.c. Jagadish: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  Ashita Dsouza: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  
• Abstract:

  Background

  Cyclobenzaprine (CBZ) a widely prescribed skeletal muscle relaxant shows poor oral bioavailability due to extensive first pass metabolism. Moreover it exhibits adverse effects particularly dizziness and drowsiness

  Methods

  The films were fabricated with HPMC and were impregnated with nanoemulsion of CBZ.  A series of nanoemulsions were
  ..

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