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Nanoemulsion impregnated films for the transdermal delivery of cyclobenzaprine

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: LEWIS, Shaila (Manipal College of Pharmaceutical Sciences, Pharmaceutics)
  • Co-author(s): Shaila Angela Lewis
    Soniya Kumbham: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
    M Vivek Ghate: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
    P.c. Jagadish: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
    Ashita Dsouza: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal, India
  • Abstract:

    Background

    Cyclobenzaprine (CBZ) a widely prescribed skeletal muscle relaxant shows poor oral bioavailability due to extensive first pass metabolism. Moreover it exhibits adverse effects particularly dizziness and drowsiness

    Methods

    The films were fabricated with HPMC and were impregnated with nanoemulsion of CBZ.  A series of nanoemulsions were

    ..

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Last update 13 May 2019

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