Comparative in vitro release profiles studies of benzoyl peroxide from different semisolids matrixes

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: ACEVEDO, Maria (ANMAT-INAME and UBA-Facultad de Farmacia y Bioquímica, Galénica y Biofarmacia / Tecnología Farmacéutica)
  • Co-author(s): Maria Eugenia Acevedo: Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica-Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
    Adriana Fernandez: Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica-Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
    Viviana Mouriño: Tecnología Farmacéutica, Facultad de Farmacia y Bioquímica-Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina;National Research and Technology Institute, CONICET, Ciudad Autonoma de Buenos Aires, Argentina
  • Abstract:

    Background

    Benzoyl Peroxide (BP) is first line drug for topical treatment of acne. BP effect is dose dependent however irritation also increases with concentration so dosage forms for a slow and constant release of drug would be advantageous.


    Methods

    A commercial emulgel formula (F1), a conventional Carbomer® 940 gel (F2) and a lipogel with

    ..

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