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Pharmacokinetical analysis of telithromycin in lung for safe therapy of respiratory infections

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Poster
  • By: MORIMOTO, Kazuhiro (Hokkaido Pharmaceutical University, Otaru, Japan)
  • Co-author(s): Togami, Kouhei (Hokkaido Pharmaceutical University, OTARU, Japan)
    Chono, Sumio (Hokkaido Pharmaceutical University, OTARU, Japan)
    Saso, Yuko (Hokkaido Pharmaceutical University, OTARU, Japan)
    Seki, Toshinobu (Hokkaido Pharmaceutical University, OTARU, Japan)
  • Abstract:

    Purpose. Telithromycin (TEL), a ketolide antibiotic agent, has a wide antimicrobial spectrum against bacterial pathogens of respiratory infection and high distribution characteristics from blood to lung. For safe therapy of respiratory infections, the pharmacokinetics of TEL from blood to lung surface and alveolar macrophages (AMs) were examined.

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Last update 4 October 2019

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