The high-throughput taqman pcr-based cyp2d6 snp and cnv genotyping without dna purification

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: KISOI, Madoka (Mukogawa Woman's University, Pharmacy)
  • Co-author(s): Madoka Kisoi
    Miho Imai
    Miwako Moritsugu
    Shigenori Murata
    Kenji Kinoshita: Pharmaceutical Sciences, Mukogawa Woman's University, Nishinomiya, Japan
  • Abstract:

    Background

    The cytochrome P450 2D6 (CYP2D6) is an important drug metabolizing enzyme that is involved in the metabolism of 20-25% of commonly prescribed drugs. Genetically, CYP2D6 is highly polymorphic, and the variants are single nucleotide polymorphism (SNP), as well as copy number variation (CNV) resulting from CYP2D6 gene deletion or..

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