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Drug gability evaluation of a protamine-like peptide

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: WU, Zhuona (Beijing Institute of Radiation Medicine, Department of Pharmacology and Toxicology)
  • Co-author(s): Zhuona Wu
  • Abstract:

    Background

    Protamine (Protamine sulfate, PS) is a highly cationic arginine-rich peptide isolated from sperm of the salmonidae or clupeidae family. PS which is widely used as an UFH antidote. PS, which possessed good efficacy, however, has many adverse effects including systematic hypotension, anaphylactic reaction, anaphylactoid reactions and..

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Last update 21 September 2019

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