Association between abcc8 rs757110 (ser1369ala) gene polymorphism and sulphonylurea response in malaysian type 2 diabetes patients

  • At: 2017 FIP Congress in Seoul (South Korea)
  • Type: Presentation
  • By: LOGANADAN, Navin Kumar (University of Malaya, Pharmacy, KUALA LUMPUR, Malaysia)
  • Co-author(s): Navin Kumar Loganadan: Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
    Hasniza Zaman Huri: Pharmacy, University of Malaya, Kuala Lumpur, Malaysia
    Shireene Ratna Vethakkan: Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Zanariah Hussein: Medicine, Putrajaya Hospital, Putrajaya, Malaysia
  • Abstract:

    Methods

    This cross-sectional study at seven outpatient clinics across Malaysia from September 2014 to March 2016 recruited 341 T2D patients receiving 20mg/day glibenclamide or 360mg/day gliclazide in combination with metformin. Their glycemic parameters were measured, DNA extracted and genotyping performed using Taqman genotyping assay (Applied

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