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Systems pharmacology models to assess immunogenicity

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: VICINI, Paolo (MedImmune, Clinical Pharmacology and DMPK, Cambridge, United Kingdom)
  • Co-author(s): Paolo Vicini: Clinical Pharmacology and DMPK, MedImmune, Cambridge, United Kingdom
  • Abstract:

    Immunogenicity is an unwanted immune system reaction that can affect biologic drugs' pharmacokinetics (PK) and pharmacodynamics (PD) [1]. Quantitative systems pharmacology (QSP), an emerging discipline which applies systems biology principles to the study of drugs [2], seeks to characterize drug action in living systems using computer models and


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Last update 4 October 2019

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