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Dose selection in phase I clinical trials in oncology

  • At: Stockholm (Sweden) (2017)
  • Type: Presentation
  • By: SCHELLENS, Jan (Netherlands Cancer Institute & University Utrecht, Clinical Pharmacology, Amsterdam, Netherlands)
  • Co-author(s): Jan HM Schellens: Clinical Pharmacology, Netherlands Cancer Institute & University Utrecht, Amsterdam, Netherlands
  • Abstract:

    Phase I studies in oncology are often carried out in patients with advanced cancer with the aim the select a safe dose and schedule for further testing in later phase II and III studies. Selection of the wrong dose and schedule can kill a good drug, which is a waist for patients and the pharmaceutical industry. Cabozantonib is a RET inhibitor


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Last update 4 October 2019

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