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Non-invasive detection of target engagement at the sub-cellular level using next generation optical tools

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: ARP, Zane (GlaxoSmithKline, BioImaging, Spring City, United States)
  • Co-author(s): Zane Arp: BioImaging, GlaxoSmithKline, King Of Prussia, United States
  • Abstract:

    One key to success for drug development is identification of drug engagement with a target.  Target engagement is often observed through ancillary information using a variety of different techniques such as fluorescent labeling, chemical biomarkers, or morphologic changes to the system.  The reliability of each of these markers is often an issue

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Last update 4 October 2019

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