Non-invasive detection of target engagement at the sub-cellular level using next generation optical tools
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Presentation
- By: ARP, Zane (GlaxoSmithKline, BioImaging, Spring City, United States)
- Co-author(s): Zane Arp: BioImaging, GlaxoSmithKline, King Of Prussia, United States
One key to success for drug development is identification of drug engagement with a target. Target engagement is often observed through ancillary information using a variety of different techniques such as fluorescent labeling, chemical biomarkers, or morphologic changes to the system. The reliability of each of these markers is often an issue.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.