Dissolution/release and permeation – impact of bile
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Presentation
- By: YAMASHITA, Shinji (Setsunan University, College of Pharmacy, Osaka, Japan)
- Co-author(s): Shinji Yamashita: College of Pharmacy, Setsunan University, Osaka, Japan
Food intake stimulates the secretion of bile and gives a great impact on the oral absorption of various drugs. Absorption of Class 2 drugs mostly undergoes positive food effect while that of Class 3 drugs does negative one. Since the current strategy of drug discovery often produces drug candidates with poor membrane permeability or poor.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.