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3D label-free imaging of drug uptake into cells and bacteria using secondary ion mass spectrometry.

  • In: Symposium B1: Towards understanding compound disposition at ever higher spatial resolution by label free methods on Monday, 22 May 2017, 16:05-16:35
  • At: Stockholm (Sweden) (2017)
  • Type: Presentation
  • By: RAKOWSKA, Paulina (National Physical Laboratory, National Centre of Excellence in Mass Spectrometry Imaging, Teddington, United Kingdom)
  • Co-author(s): Paulina Dominika Rakowska: National Centre of Excellence in Mass Spectrometry Imaging, National Physical Laboratory, Teddington, United Kingdom
  • Abstract:

    To improve the efficacy of potential drug candidates and reduce late stage failure, there is a strong need in the pharmaceutical industry to image the disposition of drugs at the sub-cellular level. Novel methodologies are necessary to investigate the penetration, accumulation and effects of the drugs in single cells, tissues, bacteria and

    ..

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Last update 28 September 2023

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