3D label-free imaging of drug uptake into cells and bacteria using secondary ion mass spectrometry.
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Presentation
- By: RAKOWSKA, Paulina (National Physical Laboratory, National Centre of Excellence in Mass Spectrometry Imaging, Teddington, United Kingdom)
- Co-author(s): Paulina Dominika Rakowska: National Centre of Excellence in Mass Spectrometry Imaging, National Physical Laboratory, Teddington, United Kingdom
To improve the efficacy of potential drug candidates and reduce late stage failure, there is a strong need in the pharmaceutical industry to image the disposition of drugs at the sub-cellular level. Novel methodologies are necessary to investigate the penetration, accumulation and effects of the drugs in single cells, tissues, bacteria and.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.