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Recent progress in formulation approaches for oral absorption of biopharmaceuticals

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Presentation
  • By: BRAYDEN, David (University College Dublin, Conway Institute, Dublin, Ireland)
  • Co-author(s): David Brayden: Conway Institute, University College Dublin, Dublin, Ireland
  • Abstract:

    Oral delivery of macromolecules remains a great challenge as it requires stability in the GI tract, delivery to the correct intestinal region, adequate epithelial permeability, and avoidance of liver first pass metabolism - all with a process that can be scaled for manufacturing.  For peptides, some of the problems may be addressed by lower

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Last update 4 October 2019

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