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Assessing food effect in vitro by use of the Dynamic Gastric Model.

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: MULLERTZ, Anette (University of Copenhagen, Pharmacy, Copenhagen Ø, Denmark)
  • Co-author(s): Lasse Saaby: Bioneer: FARMA, Bioneer A/S, Copenhagen, Denmark
    Vibeke Dalhoff: Bioneer A/S, Denmark
    Anette mullertz: Pharmacy, University of Copenhagen, Copenhagen, Denmark
  • Abstract:

    Backgrounds

    Food effect is a problem for many poorly soluble drugs. Many attempts to identify in vitro models predicting food effect have failed. The Dynamic Gastric model (DGM) is an in vitro model designed to simulate the human stomach with regards to shear forces, pH changes, enzymes and food mixing. The DGM can accommodate meal sizes from a

    ..

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Last update 4 October 2019

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