Pharmacokinetic-pharmacodynamic modeling of repeated time-to-rescue analgesia after cardiac surgery

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-E-012-Monday
• By: GOULOOZE, Sebastiaan (Leiden Academic Centre for Drug Research, Pharmacology, Leiden, Netherlands)
• Co-author(s): Sebastiaan Goulooze: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
  Elke Krekels: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
  Sabine Ahlers: Clinical Pharmacy, Gelre Hospital, Apeldoorn, Netherlands
  Mohammed Saleh: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
  Pyry Välitalo: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
  Dick Tibboel: Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands
  Catherijne Knibbe: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands;Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, Netherlands
  
• Abstract:

  Backgrounds

  Despite standardized analgesia protocols, many patients still require rescue analgesia to alleviate postoperative pain. Individualized analgesia might therefore contribute to better pain management.

  Aims

  To characterize the occurrence of rescue analgesia after cardiac surgery, using pharmacokinetic-pharmacodynamic modeling.

  Methods

  Data on
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