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Pharmacokinetic-pharmacodynamic modeling of repeated time-to-rescue analgesia after cardiac surgery

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: GOULOOZE, Sebastiaan (Leiden Academic Centre for Drug Research, Pharmacology, Leiden, Netherlands)
  • Co-author(s): Sebastiaan Goulooze: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
    Elke Krekels: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
    Sabine Ahlers: Clinical Pharmacy, Gelre Hospital, Apeldoorn, Netherlands
    Mohammed Saleh: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
    Pyry Välitalo: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands
    Dick Tibboel: Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands
    Catherijne Knibbe: Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands;Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, Netherlands
  • Abstract:

    Backgrounds

    Despite standardized analgesia protocols, many patients still require rescue analgesia to alleviate postoperative pain. Individualized analgesia might therefore contribute to better pain management.

    Aims

    To characterize the occurrence of rescue analgesia after cardiac surgery, using pharmacokinetic-pharmacodynamic modeling.

    Methods

    Data on

    ..

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Last update 4 October 2019

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