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pH Sensitive Solid Lipid Nanoparticles of Linagliptin using
Quality by Design approach for the treatment of Diabetes Mellitus

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: VENI, D. Krishna (JSS College of Pharmacy, Pharmaceutics, Mysuru, India)
  • Co-author(s): D. Krishna Veni: Pharmaceutics, JSS College of Pharmacy, Mysuru, India
    N. Vishal Gupta: Pharmaceutics, JSS College of Pharmacy, Mysuru, India
  • Abstract:


    Linagliptin is a DPP-4 Inhibitor used in the treatment of Type II Diabetes. One of the major challenges of this drug was found to be degradation in the gastric environment which lead to low bioavailability. In this study to overcome this challenge drug has been enteric coated with a pH sensitive polymer and formulated as solid lipid


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Last update 4 October 2019

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