Pre-junctional effects of oximes on [3h]-acetylcholine release in rat hippocampal slices during soman intoxication.
- At: 2007 FIP Congress in Beijing (China)
- Type: Poster
- By: ØYDVIN, Ole Kristian (Apotek 1 Triaden, LØrenskog, Norway)
- Co-author(s): Aas, Pål (Norwegian Defence Research Establishment, 2027 KJELLER, Norway)
In this study, the non-reactivating effects of oximes in the hippocampus of the rat are investigated. The potassium (51 mM) evoked release of [3H]-acetylcholine and the liberation of [3H]-choline were determined in hippocampal slices following in vitro exposure to soman and five oximes (toxogonin, HI-6, HLÃ¶-7, P2S and 2-PAM) in separate.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.