Pre-junctional effects of oximes on [3h]-acetylcholine release in rat hippocampal slices during soman intoxication.

• In: Military and Emergency Pharmacy Section - Posters
• At: Beijing (China) (2007)
• Type: Poster
• Poster code: MEPS-P-006
• By: ØYDVIN, Ole Kristian (Apotek 1 Triaden, LØrenskog, Norway)
• Co-author(s): Aas, Pål (Norwegian Defence Research Establishment, 2027 KJELLER, Norway)
  
• Abstract:

  In this study, the non-reactivating effects of oximes in the hippocampus of the rat are investigated. The potassium (51 mM) evoked release of [3H]-acetylcholine and the liberation of [3H]-choline were determined in hippocampal slices following in vitro exposure to soman and five oximes (toxogonin, HI-6, HLö-7, P2S and 2-PAM) in separate..

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