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Determination and quantification of Alendronate Sodium Trihydrate within the inner aqueous phase of w/o/w double emulsions intended for oral use

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: ABD JALIL, Muhammad Fauzi (UCL School of Pharmacy, Pharmaceutics, London, United Kingdom)
  • Co-author(s): Muhammad Fauzi Abd Jalil: UCL School of Pharmacy, London, United Kingdom;, Universiti Teknologi Malaysia , Johor Bahru , Malaysia
    Susan Barker: UCL School of Pharmacy, London, United Kingdom
  • Abstract:

    Backgrounds

    Biopharmaceutics Classification System (BCS) Type III drugs are challenging to formulate for oral use, as their oral absorption and hence bioavailability (BA) are low. For example, alendronate sodium trihydrate (ALD) has only 0.7% BA and therefore a high oral dose of ALD (10 mg/day or 70 mg/week) is required to be given for treatment of

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Last update 4 October 2019

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