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The impact of dissolution in the lower intestine on the absorption of high dose low solubility drugs

  • In: Poster Presentation
  • At: Stockholm (Sweden) (2017)
  • Type: Poster
  • Poster code: P-C-073-Monday
  • By: VERTZONI, Maria (National and Kapodistrian University of Athens, Pharmacy, Athens, Greece)
  • Co-author(s): Danai Georgaka: Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
    James Butler: Product Development, GlaxoSmithKline, Ware, United Kingdom
    Filippos Kesisoglou: Pharmaceutical Sciences and Clinical Supply, Merck & Co., Inc., Kenilworth, United States
    Christos Reppas: Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
    Maria Vertzoni: Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
  • Abstract:

    Backgrounds

    This work was performed within the OrBiTo project funded by the IMI Joint Undertaking under Grant Agreement No 115369.

    Aims

    Τo evaluate the impact of dissolution in the lower intestine on the absorption of three model, high dose, low solubility drugs, i.e. micronized aprepitant, SB705498 [Immediate release tablets (25mg/tab) and Capsules

    ..

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Last update 28 September 2023

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