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Effect of monoacyl phospholipid on the in vitro and in vivo performance of self-emulsifying drug delivery systems

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: TRAN, Thu Thuy (University of Copenhagen, Department of Pharmacy, Copenhagen, Denmark)
  • Co-author(s): Thu Thuy Tran: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
    Scheyla D.V.S Siqueira: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
    Heinz Amenitsch: Institute of Inorganic Chemistry, Graz University of Technology, Graz, Austria
    Thomas Rades: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
    Anette Müllertz: Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark
  • Abstract:

    Backgrounds

    Self-emulsifying drug delivery systems (SEDDS) have been used to enhance the oral bioavailability of lipophilic drugs.

    Aims

    This study investigates the effect of monoacyl phospholipid on the in vitro and in vivo performance of SEDDS containing fenofibrate (FF).

    Methods

    In vitro lipolysis of SEDDS (Table 1) was performed in simulated human

    ..

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Last update 4 October 2019

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