Structuring and Drug Interactions in Lipid-Based Formulations Studied by Coarse Grained Molecular Dynamics Simulations
- At: Stockholm (Sweden) (2017)
- Type: Poster
- By: LARSSON, Per (Uppsala University, Pharmacy, Uppsala, Sweden)
- Co-author(s): Per Larsson: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Christel A S Bergström: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Oral administration of drugs requires sufficient solubility of the active ingredient in intestinal fluid to allow complete absorption. Modern drug discovery techniques often generate lead compounds with low aqueous solubility in need of enabling formulations.
To explore whether coarse-grained (CG) molecular dynamics (MD) methodology.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.