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Solid dispersions tadalafil-Soluplus® formed by high-energy ball milling.
Impact of process parameters.

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KRUPA, Anna (Jagiellonian University, Medical College, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmaceutics, Krakow, Poland)
  • Co-author(s): Anna Krupa: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
    Dorota Majda: Faculty of Chemistry, Jagiellonian University, Krakow, Poland
    Katarzyna Dziewic: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
    Renata Jachowicz: Pharmaceutical Technology and Biopharmaceutics, Jagiellonian University Medical College Faculty of Pharmacy, Krakow, Poland
  • Abstract:

    Backgrounds

    Tadalafil is a high melting point poorly soluble drug. Thus, the amorphisation methods, which can be carried out at room temperature, and are organic solvents-free need to be optimized with the aim to improve its solubility.

    Aims

    The aim of this study was to investigate the impact of high-energy ball milling process parameters: (i)

    ..

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Last update 4 October 2019

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