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The Effect of the Physiological Parameters of the Gastrointestinal Fluid on Quetiapine Fumarate Release from Matrix Tablets Prepared Using Two Different Polymeric Blends
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: HAMED, Rania (Al-Zaytoonah University of Jordan, Pharmacy, Amman, Jordan)
- Co-author(s): Rania Hamed: Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
Reem AlJanabi: Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
Aiman Abbas: Research and Development, Hikma Pharmaceuticals, Amman, Jordan
Suhair Sunoqrot : Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
BackgroundsThe physiological parameters of gastrointestinal (GI) fluids (pH, buffer capacity, and ionic strength) are critical for the performance of polymers used in formulating controlled-release matrix tablets.
To investigate the effect of the physiological parameters of the GI fluid on the in vitro release of the weakly basic BCS class II.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019