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The Effect of the Physiological Parameters of the Gastrointestinal Fluid on Quetiapine Fumarate Release from Matrix Tablets Prepared Using Two Different Polymeric Blends

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: HAMED, Rania (Al-Zaytoonah University of Jordan, Pharmacy, Amman, Jordan)
  • Co-author(s): Rania Hamed: Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
    Reem AlJanabi: Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
    Aiman Abbas: Research and Development, Hikma Pharmaceuticals, Amman, Jordan
    Suhair Sunoqrot : Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan
  • Abstract:

    Backgrounds

    The physiological parameters of gastrointestinal (GI) fluids (pH, buffer capacity, and ionic strength) are critical for the performance of polymers used in formulating controlled-release matrix tablets.

    Aims

    To investigate the effect of the physiological parameters of the GI fluid  on the in vitro release of the weakly basic BCS class II

    ..

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Last update 4 October 2019

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