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Continuous wet granulation - the effect of the drying scale on granule and tablet properties

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: CLARK, Richard (AstraZeneca, Pharmaceutical technology & development, Macclesfield, United Kingdom)
  • Co-author(s): Richard Clark: Pharmaceutical technology & development , AstraZeneca, Gothenburg, Sweden
    Lina Kronsell: Pharmaceutical technology & development , AstraZeneca, Gothenburg, Sweden
    Jonas Odman: Pharmaceutical technology & development , AstraZen
  • Abstract:

    Backgrounds

    Continuous wet granulation can offer a solution to scale-up problems as it is able to process both small and large batches on the same equipment by extending the run time. 

    Aims

    The aim of the study was to determine whether the scale of drying impacts granule and tablet properties; whilst assessing process stability.

    Methods

    The Consigma-25

    ..

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Last update 4 October 2019

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