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Investigation of supersaturation and permeation of a poorly water soluble drug Ezetimibe

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: AL-HAYALI, Amani (Lulea University of Technology, Lulea university of technology, Luleå, Sweden)
  • Co-author(s): Amani Al-Hayali: Lulea University of Technology, Luleå, Sweden
    Mohammed Ali Selo: School of Pharmacy and Pharmaceutical Sciences , Trinity College Dublin , Ireland
    Carsten Ehrhardt: School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland
    Sitaram Velaga: Lulea University of Technology, Luleå, Sweden
  • Abstract:

    Backgrounds

    Newly developed formulations of the poorly soluble drugs are designed to create supersaturation in vivo. The flux across the intestinal membrane can influence precipitation kinetics of a supersaturated phase. Thus, it is important to understand the interplay among supersaturation-precipitation-permeability in the development of..

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Last update 4 October 2019

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