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Blood-brain barrier transport and intra-brain distribution of the cyclotide kalata B1

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: MELANDER, Erik (Uppsala, Sweden)
  • Co-author(s): Erik Melander: Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
    Camilla Eriksson: Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden
    Ulf Göransson: Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden
    Margareta Hammarlund-Udenaes: Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
  • Abstract:

    Backgrounds

    Cyclotides are a group of stable cyclic peptides containing three disulphide bonds. They are interesting from a drug development perspective, as they can be used as a scaffold for stabilizing linear peptides. One area that would benefit from improved characteristics of therapeutic peptides is the CNS. Therapeutic peptide generally have..

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Last update 4 October 2019

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