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Distribution of model macromolecule drug in whole brain, nasal mucosa, and trigeminal nerve in rats after intranasal administration with basic peptide based nanocarriers

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KANAZAWA, Takanori (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
  • Co-author(s): Takanori Kanazawa: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
    Mami Kaneko: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
    Takaki Niide: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
    Hisako Ibaraki: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
    Yuuki Takashima: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
    Yasuo Seta: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  • Abstract:

    Backgrounds

    Nose-to-brain delivery is a highly versatile route, which, in combination with novel drugs, is a promising approach  for intractable CNS disorders. Furthermore, nano-sized drug carriers may improve nose-to-brain drug delivery.

    Aims

    To investigate the nose-to-brain pathway using nanocarriers, the time-dependent distribution of model

    ..

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Last update 4 October 2019

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