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Effect of an enhanced nose-to-brain delivery of insulin on mild and progressive memory loss in the senescence-accelerated mouse

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KAMEI, Noriyasu (Kobe Gakuin University, Faculty of Pharmaceutical Sciences, Kobe, Japan)
  • Co-author(s): Noriyasu Kamei: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
    Misa Tanaka: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
    Hayoung Choi: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
    Nobuyuki Okada: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
    Takamasa Ikeda: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
    Mariko Takeda-Morishita: Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan
  • Abstract:

    Backgrounds

    Insulin is now considered to be a new drug candidate for treating dementias, such as Alzheimer’s disease, whose pathologies are linked to insulin resistance in the brain.  Our recent work has clarified that a noncovalent strategy involving cell-penetrating peptides (CPPs) can increase the direct transport of insulin from the nasal..

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Last update 4 October 2019

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