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Impact of lipids on intracellular bioavailability
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: TREYER, Andrea (Uppsala University, Pharmacy, Uppsala, Sweden)
- Co-author(s): Andrea Treyer: Pharmacy, Uppsala University, Uppsala, Sweden
André Mateus: Pharmacy, Uppsala University, Uppsala, Sweden
Hinnerk Boriss: Sovicell GmbH, Leipzig, Germany
Pär Matsson: Pharmacy, Uppsala University, Uppsala, Sweden
Per Artursson: Pharmacy, Uppsala University, Uppsala, Sweden
BackgroundsIntracellular unbound drug concentration (Cu,cell) drives pharmacological and toxicological responses for targets inside cells. However, the mechanisms that drive cellular drug binding are not so well understood.
AimsThe aim of this study was to evaluate drug binding to two cellular components - neutral lipids and phospholipids.
MethodsBin.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019