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Ion Pair Formation to Augment Oral Absorption of Enoxaparin

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: PAULETTI, Giovanni (University of Cincinnati, Winkle College of Pharmacy, Cincinnati, United States)
  • Co-author(s): Nermin Eleraky: Faculty of Pharmacy, Assiut University, Assiut , Egypt
    Giovanni Pauletti: Winkle College of Pharmacy, University of Cincinnati, Cincinnati, United States
  • Abstract:

    Backgrounds

    Enoxaparin (EXP) is conventionally administered by injection as this anticoagulant exhibits limited permeation across biological membranes.

    Aims

    This research explores hydrophobic ion pairing as a novel strategy for augmenting bioavailability of EXP after oral absorption.

    Methods

    Binding enthalpies of EXP/cetyltrimethylammonium bromide

    ..

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Last update 4 October 2019

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