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Biological activity of isoniazid chitosan microparticles in alveolar macrophages

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: OLIVEIRA, Paula (University of Brasília, Faculty of Health Sciences, Brasília, Brazil)
  • Co-author(s): Paula Oliveira: LTMAC, University of Brasília, Brasília, Brazil
    Priscilla Pereira: FCFRP, Universidade de São Paulo, Ribeirão Preto, Brazil
    Breno Noronha: LTMAC, University of Brasília, Brasília, Brazil
    Tais Gratieri: LTMAC, University of Brasília, Brasília, Brazil
    Lucia Faccioli: FCFRP, Universidade de São Paulo, Ribeirão Preto, Brazil
    Marcílio Cunha-Filho: LTMAC, University of Brasília, Brasília, Brazil
    Guilherme Gelfuso: LTMAC, University of Brasília, Brasília, Brazil
  • Abstract:

    Backgrounds

    Tuberculosis current treatment is systemic and required high doses of drugs that cause several adverse effects.

    Aims

    This study aimed to obtain and characterize isoniazid (INH) loaded chitosan microparticles (MPs) to pulmonary route and to evaluate in vitro their biological activities in alveolar macrophages.

    Methods

    MPs were prepared with

    ..

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Last update 4 October 2019

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