Biometals regulate the expression and function of P-glycoprotein at the blood-brain barrier
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: NICOLAZZO, Joseph (Monash University, Drug Delivery, Disposition and Dynamics, Parkville, Australia)
- Co-author(s): Joseph Nicolazzo: Drug Delivery, Disposition and Dynamics, Monash University, Parkville, Australia
Mitchell McInerney: Drug Delivery, Disposition and Dynamics, Monash University, Parkville, Australia
Jennifer Short: Drug Discovery Biology, Monash University, Parkville, Australia
The biometals copper (Cu2+) and zinc (Zn2+) are essential for normal brain health and any imbalance in their levels leads to neurological disease. The role of these biometals in the health of the blood-brain barrier (BBB), however, has received little attention.
AimsTo assess the impact of Cu2+ and Zn2+ on the expression and function of.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.