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Effects of phenylpropanoids on renal organic anion transporters OAT1 and OAT3

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KAWASAKI, Tatsuya (School of Pharmacy, Aichi Gakuin University, Nagoya, Aichi, Japan)
  • Co-author(s): Tatsuya Kawasaki: School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    Yoshiyasu Takeichi: School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    Masashi Tomita: School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    Yuichi Uwai: School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
    Tomohiro Nabekura: School of Pharmacy, Aichi Gakuin University, Nagoya, Japan
  • Abstract:

    Backgrounds

         Human organic anion transporter 1 and 3 (OAT1/SLC22A6; OAT3/SLC22A8) are highly expressed at the basolateral membrane in the renal proximal tubular cells, and mediate tubular uptake of diverse anionic drugs from blood.  Therefore, they govern renal elimination of the drugs.


         Phenylpropanoids are known for beneficial effects such


    ..

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Last update 4 October 2019

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