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Involvement of P-glycoprotein in transdermal absorption of its substrates including topical corticosteroids

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KATO, Yukio (Kanazawa University, Faculty of Pharmacy, Kanazawa, Japan)
  • Co-author(s): Naoto Hashimoto: Faculty of Pharmacy, Kanazawa University, Kanazawa, Japan
    Noritaka Nakamichi: Faculty of Pharmacy, Kanazawa University, Kanazawa, Japan
    Yusuke Masuo: Faculty of Pharmacy, Kanazawa University, Kanazawa, Japan
    Yukio Kato: Faculty of Pharmacy, Kanazawa University, Kanazawa, Japan
  • Abstract:

    Backgrounds

    ATP binding cassette transporters, P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), are expressed in skin, but their roles in transdermal absorption of their substrates remains largely unknown. 

    Aims

    The purpose of the present study was to examined their possible involvement in transdermal absorption of rhodamine 123

    ..

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Last update 4 October 2019

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