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Investigation of pulmonary drug permeability and tissue retention by computational analysis of rat ex vivo lung absorption profiles
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: ERIKSSON, Johanna (Uppsala University, Department of Pharmacy, Uppsala, Sweden)
- Co-author(s): Johanna Eriksson: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Erik Sjögren: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Helena Thörn: Pharmaceutical Development Inhalation, AstraZeneca-Gothenburg, Gothenburg, Sweden
Katarina Rubin: Respiratory, Inflammation and Autoimmunity, Innovative Medicine and Early Development, AstraZeneca-Gothenburg, Gothenburg, Sweden
Per Bäckman: Current adress: Mylan Global Respiratory Group, Mylan Pharma UK Ltd, Kent, United Kingdom;Pharmaceutical Development Inhalation, AstraZeneca-Gothenburg, Gothenburg, Sweden
Hans Lennernäs: Department of Pharmacy, Uppsala University, Uppsala, Sweden
BackgroundsTo achieve an optimal drug delivery to the lung by pharmaceutical formulation it is important to have knowledge not only about residence time and drug release, but also of the rate and mechanisms of pulmonary permeability and tissue retention processes.
AimsThe aim of this study was to investigate the overall pulmonary absorption of drug .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019