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Changes in Indomethacin Solubility in Mixtures with Basic Drugs
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: SHIMADA, Yohsuke (Tokyo University of Science, Faculty of Pharmaceutical Sciences, Noda, Japan)
- Co-author(s): Yohsuke Shimada: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan
Ryo Tateuchi: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan
Satoru Goto: Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan
BackgroundsA mixture of indomethacin (IND), an acidic nonsteroidal anti-inflammatory drug, and lidocaine (LID), a local anesthetic (LA), forms a eutectic complex, which has a low melting point that is near room temperature. The aqueous solubility of the mixture is greater than that of IND or LID alone, improving the bioavailability of IND.
AimsTher.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019