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Supersaturated Silica Lipid Hybrids (Super-SLH): Solid State Lipid Based Drug Delivery Systems with Improved Drug Loading

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: SCHULTZ, Hayley (University of South Australia, School of Pharmacy and Medical Science, Adelaide, Australia)
  • Co-author(s): Hayley Schultz: School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia
    Nicky Thomas: School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia
    Shasha Rao: School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia
    Clive Prestidge: School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia
  • Abstract:

    Backgrounds

    Lipid based drug delivery systems (LBDDS) can improve the oral delivery of poorly water-soluble drugs, however their application is frequently limited by low drug loading (typically 1-10% w/w).

    Aims

    It was hypothesised that encapsulating drug supersaturated in lipid within porous silica microparticles would inhibit drug precipitation and

    ..

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Last update 4 October 2019

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