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The phosphorylation of alpha-tocopherol facilitates enhanced interactions with skin lipids

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: SALEH, Mais (King's College London, Institute of Pharmaceutical science, London, United Kingdom)
  • Co-author(s): Mais Saleh: Institute of Pharmaceutical science, King's College London, London, United Kingdom
    Arcadia Wood: Institute of Pharmaceutical science, King's College London, London, United Kingdom
    Richard Harvey: Institute of Pharmacy, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany
    Stuart Jones: Institute of Pharmaceutical Science, King's College London, London, United Kingdom
  • Abstract:

    Backgrounds

    Tocopherol phosphate (TP) is an amphiphilic water-soluble form of vitamin E (T). 

    Aims

    The aim was to study the interactions between TP and the skin using a stratum corneum(SC) lipid model composed of equimolar mixtures of ceramide, cholesterol, and palmitic acid.

    Methods

    The Langmuir trough was used to acquire surface pressure-molecular

    ..

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Last update 4 October 2019

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