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Investigation on the thermal behaviour of doxorubicin sulphate nanocrystals in Doxil® liposomal formulation

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: PERINELLI, Diego Romano (University of Camerino, Camerino, Italy)
  • Co-author(s): Diego Romano Perinelli: School of Pharmacy, University of Camerino, Camerino, Italy
    Giulia Bonacucina: School of Pharmacy, University of Camerino, Camerino, Italy
    Marco Cespi: School of Pharmacy, University of Camerino, Camerino, Italy
    Luca Casettari: Department of biomolecular sciences, University of Urbino, Urbino, Italy
    Giovanni Filippo Palmieri: School of Pharmacy, University of Camerino, Camerino, Italy
  • Abstract:

    Backgrounds

    Liposomes are nano-sized lipid bilayer vesicles of great interest in drug delivery. Doxil® is an example of a marketed liposomal formulation containing the anticancer drug doxorubicin. These liposomes, composed of soy phosphatidylcholine, cholesterol and PEGylated phosphoethanolamine have a stable loading of doxorubicin sulphate (DOX).

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Last update 4 October 2019

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