Molecular Dynamics simulations of colloidal structures in aspirated human intestinal fluids
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: PARROW, Albin (Uppsala University, Department of Pharmacy, Uppsala, Sweden)
- Co-author(s): Albin Parrow: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Christel A. S. Bergström: Department of Pharmacy, Uppsala University, Uppsala, Sweden
Per Larsson: Department of Pharmacy, Uppsala University, Uppsala, Sweden
To more accurately predict intestinal drug solubility the colloidal structures in the intestinal fluid is of importance. In the fasted state these are composed mainly of bile salts and phospholipids that may solubilize hydrophobic compounds significantly. One potential approach to explore these colloidal structures is by molecular.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.