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In vitro lipolysis of drug loaded lipid-based formulations with solid-state characterization of drug precipitate

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: ALSKäR, Linda (Uppsala University, Pharmacy, Uppsala, Sweden)
  • Co-author(s): Linda C. Alskär: Pharmacy, Uppsala University, Uppsala, Sweden
    Jenny Johannesson : Pharmacy, Uppsala University, Uppsala, Sweden
    Janneke Keemink: Pharmacy, Uppsala University, Uppsala, Sweden
    Christel A. S. Bergström : Pharmacy, Uppsala University, Uppsala, Sweden
  • Abstract:

    Backgrounds

    Lipid-based formulations (LBFs) are used to overcome solubility limitations and to improve oral absorption of poorly water-soluble drugs. However, during lipid dispersion and digestion in the GI tract there is a risk of drug precipitation, a process that is poorly understood.

    Aims

    The aim of this work was to study the precipitation

    ..

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Last update 4 October 2019

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