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In vitro lipolysis of drug loaded lipid-based formulations with solid-state characterization of drug precipitate
- At: Stockholm (Sweden) (2017)
- Type: Poster
- By: ALSKäR, Linda (Uppsala University, Pharmacy, Uppsala, Sweden)
- Co-author(s): Linda C. Alskär: Pharmacy, Uppsala University, Uppsala, Sweden
Jenny Johannesson : Pharmacy, Uppsala University, Uppsala, Sweden
Janneke Keemink: Pharmacy, Uppsala University, Uppsala, Sweden
Christel A. S. Bergström : Pharmacy, Uppsala University, Uppsala, Sweden
BackgroundsLipid-based formulations (LBFs) are used to overcome solubility limitations and to improve oral absorption of poorly water-soluble drugs. However, during lipid dispersion and digestion in the GI tract there is a risk of drug precipitation, a process that is poorly understood.
AimsThe aim of this work was to study the precipitation.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019