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Statin promotes macrophage efferocytosis and inhibits atherosclerosis

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: HEO, Kyung-Sun (Chungnam National University, College of Pharmacy, Pharmacology, Daejeon, Korea, Republic Of)
  • Co-author(s): Kyung-Sun Heo: College of Pharmacy, Pharmacology, Chungnam National University, Daejeon, Korea, Republic Of
    Chang-Seon Myung: College of Pharmacy, Pharmacology, Chungnam National University, Daejeon, Korea, Republic Of
    Jun-Ichi Abe: Department of Cardiology, University of Texas MD Anderson Cancer Center, Houston, United States
  • Abstract:

    Backgrounds

    Efferocytosis is a process by which dead and dying cells are removed by phagocytic cells. Efferocytosis by macrophages is thought to curb the progression of atherosclerosis, but the mechanistic insight of this process is lacking. 

    Aims

    To understand the role and molecular mechanisms of statin, the role of macrophage ERK5, as the strongest

    ..

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Last update 4 October 2019

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