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Statin promotes macrophage efferocytosis and inhibits atherosclerosis
- At: 2017 FIP Congress in Stockholm (Sweden)
- Type: Poster
- By: HEO, Kyung-Sun (Chungnam National University, College of Pharmacy, Pharmacology, Daejeon, Korea, Republic Of)
- Co-author(s): Kyung-Sun Heo: College of Pharmacy, Pharmacology, Chungnam National University, Daejeon, Korea, Republic Of
Chang-Seon Myung: College of Pharmacy, Pharmacology, Chungnam National University, Daejeon, Korea, Republic Of
Jun-Ichi Abe: Department of Cardiology, University of Texas MD Anderson Cancer Center, Houston, United States
BackgroundsEfferocytosis is a process by which dead and dying cells are removed by phagocytic cells. Efferocytosis by macrophages is thought to curb the progression of atherosclerosis, but the mechanistic insight of this process is lacking.
AimsTo understand the role and molecular mechanisms of statin, the role of macrophage ERK5, as the strongest .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 4 October 2019