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Studies on the Electrophysiological Mechanism of IMM-302 to Improve Learning and Memory in animal model

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: GUO, Tingting (Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Pharmacology, Beijing, China)
  • Co-author(s): Tingting Guo: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Xiaomei Jiang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Weiping Wang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Xiaoliang Wang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  • Abstract:

    Backgrounds

     IMM-302 exhibited the therapeutic effects on cognitive deficits in the preclinical studies. However, the mechanisms of IMM-302 are still unknown.

    Aims

    In this study, we investigated the effects of IMM-302 on ion channels related to GABAA, NMDA and AMPA receptors. 

    Methods

    1) Morris water maze test was used to evaluate the behavior of

    ..

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Last update 4 October 2019

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