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Inhibition of mitochondrial fission drives protective M2 microglia polarization: the role of ruscogenin in the amelioration of ischemia/reperfusion injury

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: KECHENG, Zhou (China Pharmaceutical University, 1. Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Nanjing, China)
  • Co-author(s): Zhou Kecheng: 1. Jiangsu Key Laboratory of TCM Evaluation and Translational Research, China Pharmaceutical University, Nanjing, China
    Kou junping: 1. Jiangsu Key Laboratory of TCM Evaluation and Translational Research, China Pharmaceutical University, Nanjing, China
  • Abstract:

    Backgrounds

    Regulating microglia polarization is a promising therapeutic strategy for stroke. The homeostasis of mitochondrial dynamic is equally important for treating stroke. However, the relationship between mitochondrial fission and microglia polarization is unclear and the effects of ruscogein, a natural steroid saponin, on mitochondrial..

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Last update 4 October 2019

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