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A novel ULK1 agonist with cytoprotective autophagy modulation in Parkinson's disease

  • At: 2017 FIP Congress in Stockholm (Sweden)
  • Type: Poster
  • By: OUYANG, Liang (Chengdu, China)
  • Co-author(s): Lan Zhang: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center for Biotherapy, Sichuan university, Chengdu, China
    Liang Ouyang: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center for Biotherapy, Sichuan University, Chengdu, China
  • Abstract:

    Backgrounds

    Autophagy is an evolutionarily conserved, multi-step lysosomal degradation process, in which a cell degrades long-lived proteins and damaged organelles. Defects in autophagy have implications for therapy of Parkinson's disease (PD), and thus activation of autophagy would be a promising strategy. UNC-51-like kinase 1(ULK1), the yeast Atg1..

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Last update 4 October 2019

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