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Correlation between Formation of Glucuronide Metabolite and Covalent Protein Adducts of Nonsteroidal Anti-inflammatory Drugs
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-027-Tuesday
- By: SHIMADA, Hiroaki (Kindai university, pharmacy, Higashi-osaka, Japan)
- Co-author(s): Hiroaki Shimada: Department of Pharmacy, Kindai University, Osaka, Japan
Atsushi Kawase: Department of Pharmacy, Kindai University, Osaka, Japan
Taro Ogiso: Department of Pharmacy, Kindai University, Osaka, Japan
Masahiro Iwaki: Department of Pharmacy, Kindai University, Osaka, Japan - Abstract:
Backgrounds
Nonsteroidal anti-inflammatory drugs (NSAIDs) sometimes cause idiosyncratic liver injury. Although previous studies have shown that complicated mechanisms are involved in NSAIDs-induced liver injury, glucuronide of NSAIDs (NSAIDs-Glu) plays important roles in developing liver injury. Especially, NSAIDs-Glu forms covalent binding with.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 28 September 2023